The Omicron outbreak marks the end of Tibet's 920-day COVID free period.
Lhasa has set up more than 500 testing points, suspended large events and closed entertainment venues.
But a Lhasa resident told us people are very calm.
"We have a lot of lot of experiences we can learn from, from Beijing, Shanghai, Guangdong.
So people are wearing masks, people do not show like very nervous, being threatened, not at all.
People are obeying the rules, wearing masks.
And the restaurant is open, the bakery is open, those grocery stores are open. Everything is pretty normal here."
餐厅在开门营业，面包店在开门营业，杂货店也在开门营业 。这里的一切都很正常 。”
Officials have announced new restrictions in high-risk areas of large cities, like Lhasa, Shigatse and other parts of the region.
Religious sites, like the Potala Palace and Jokhang Temple have been closed
and people who have not been to high-risk areas will be allowed to travel in the region with a negative test result obtained within 48 hours before departure.
It's still early days but people in Lhasa say they have no problem getting their daily necessities and there's no panic buying at supermarkets.