时差N小时:移除大肠毒素分子
日期:2012-07-24 18:17

(单词翻译:单击)

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It's three in the morning and you're awakened out of a deep sleep by a terrible pain in the gut. Was it something you ate? And then it hits you—that burger you had the other day was a little undercooked. And there have been several cases of e-coli poisoning reported in your area.
凌晨3点,熟睡中的你突然被胃部剧烈的疼痛弄醒8fZ1ODTBmh6E^。是因为吃坏肚子了吗?然后你想到昨天吃的汉堡有点生dkS3+kVk~M=b7jTZx;。这附近也报道过几起因大肠杆菌引起中毒的事件pa3[cV,5RfZHheJtv~
If you do have e-coli toxins coursing through your bloodstream, the symptoms can be distressing, particularly the bloody diarrhea. And, unfortunately, there's no antidote. All you can do is wait it out. But that may change. Scientists at the University of Alberta, in Canada, have engineered a molecule to seek out e-coli toxins in the blood and flush them out of the system.
如果你血液里含有大肠杆菌,你会出现疼痛的症状,尤其会出现带血的腹泻x0XYFbSOBQ5ei.a。不幸的是,没有解药I|x9-,.#r.kc。你能做的只有坐等情况好转w48iHjHhKD~I%f8by。但情况也许有变QU&j^iE_NKqb4^U。加拿大艾伯塔大学的科学家们研制出一种分子,这种分子能搜索出血液里大肠杆菌,并将它们稀释排出体外84cPlwR9gMO
The molecule works like a kind of molecular barb: it cruises around in the blood, and when it finds an e-coli toxin it snags the toxin and attaches it to an immune system protein. The protein then neutralizes the toxin. So far the molecule has been tested in mice and been found to be effective.
这种分子的作用类似于鱼钩:它在血液里四处巡游,一旦找到大肠杆菌,就用凸起绊住并将它粘附在免疫蛋白上LlSgD|cwZqtQobZv+3%Z。然后免疫蛋白将毒素中和掉k3,_yFwQY*d0pWM0GQ。目前为止,这种分子已经在老鼠身上试验过,效果很显著fLSgaCll9Kg~S@Nf5Vf
But because e-coli poisoning is relatively rare, it's unlikely that the molecule will be used to manufacture a marketable drug any time soon. The research is still useful, though, because it models a promising way to treat a potentially wide range of bacterial infections. For example, the e-coli toxin is shaped similarly to the cholera toxin. So there could be a molecular solution to treating cholera—a disease that affects millions of people around the world.
但是因为大肠杆菌中毒现象相对很少见,所以将这种分子大规模制成药物推向市场,还不太可能+TUQ)9Bi46Cx6yw。但是这项研究仍然有用,因为它塑造了一种有效的方式来治疗各种各样的病毒感染IFl[KZfym8~_1TQZ6PX。例如,大肠杆菌与霍乱病毒的形状类似RAU||&gM.pC0bZG0|_。全球有数百万人感染上霍乱病毒,因此也可以研发出相应的分子,来治疗霍乱gve~KS#W-i

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重点单词
  • antidoten. 解毒剂,解药 n. (喻)矫正方法
  • flushv. 奔流,发红,冲洗,迅速流过 n. 脸红,奔流,旺盛
  • promisingadj. 有希望的,有前途的
  • distressingadj. 使人痛苦的,令人烦恼的 动词词distress
  • effectiveadj. 有效的,有影响的
  • potentiallyadv. 潜在地
  • toxinn. 毒素,毒质
  • unlikelyadj. 不太可能的
  • immuneadj. 免除的,免疫的
  • solutionn. 解答,解决办法,溶解,溶液