Do you need/want some help?
Can I help you?
How can I help?
Would you like some help with that?
What do you need/want me to do?
You look like you need some help.
Let me help you with that.
A: Just let me know what you need.
B: Thanks. I really appreciate the help.
A: I'm here to help. Just let me know what you want.
B: I really appreciate this.
A: Would you care for some help with that?
B: That would be great, thanks.
A: Let me get that for you.
B: Thanks. I thought I was going to drop it.
A: Want/Need some help?
B: It's about time.