How is it going?

How is everything going?

最近怎么样？

You look in a good mood.

你看起来心情很好。

be in a good/bad mood

心情好/差

How have you been getting along?

你们相处怎么样？

get along

进展；相处

It couldn't be worse.

简直不能再糟糕了。

What have you been up to（lately）?

最近在忙什么？

I heard you're doing well.

我听说你发展的不错。

A: Good morning, Cathy.

早上好，凯西。

B: Good morning, John.

早上好，约翰。

A: You look tired, what have you been up to lately?

你看起来很疲惫，最近在忙什么呢？

B: Don't mention it. Something is wrong with one of the projects I'm in charge of, and I've been busy working on it lately. I haven't slept well in days. I just came out of company.

别提了，我负责的一个项目出了问题，我最近忙着解决这件事呢。我已经好几天没好好睡觉了，我刚从公司出来。

"Don't mention it".作“别提了”，表示对某种情况很不满或很无奈；作“别客气”解多用来对别人感谢做出回应。

"in charge of"意为“负责”，表示主动，其主语只能是人，而in the charge of意为“负责”，常用主动形式表被动，主语是事物。比如：I'm in charge of this project. This project is in the charge of me.我负责这个项目。

A: I know your work is important, but health is more important. If you go on like this, your body will break down.

我知道你的工作很重要，但是身体更重要啊，你再这样下去身体会垮掉的。

break down可以表示“身体垮掉”，“机器坏掉”等

B: Well, my problem at work has been solved. I have taken two days off and I'll have a good rest.

我工作上的问题已经解决了，我请了两天假，好好休息一下。

take days off意为“休几天假”，ask for leave意为“请假”，be on leave意为 “休假”

A: That's good. My daughter is back from abroad, and I'm going to pick her up at the airport. But what is even worse is that my car breaks down, so I have to take a taxi.

那就好，我女儿从国外回来了，我要去机场接他，但是倒霉的是我的车坏了，我只好打出租车了。

pick sb up意为“接送某人”；What is even worse意为“更糟糕的是”

B: I can drive you there.

我开车送你去。

A: Come on. You'd better go home and get some rest.

得了吧，你还是赶紧回家休息吧。

B: All right. Bye.

那好吧，再见。