原文视听

How many of you have your flu shot already this year?

你们有多少人今年已经注射过流感疫苗了?

Great

好极了

Did you get a good night sleep before you had a flu shot?

你们在注射之前睡了个好觉吗?

Or after that flu shot?

注射之后睡个好觉了吗?

There's a lot of data now that would indicate

现在有很多研究数据显示

that if you are not getting sleep

如果你没有睡好

a study of a healthy young man

对健康的年轻人的研究显示

they have deprived them of sleep to 4 hours

如果他们连续4个晚上

a night for 4 nights

只睡4个小时

then gave them the flu shot

然后再接受流感疫苗注射

The other group sleeps normally

而另一组睡眠时间正常

and 10 days later

十天之后

they have much lower titer to their flu shot response rate

和正常睡眠的小组相比

than the young healthy men who got the normal sleep time

睡眠不足的小组血液中的流感抗体要低得多

This was in 2002

这是2002年的研究结果

It's been replicated in a fair number

这个试验被重复了很多次

of other types of studies

选择的疫苗各有不同

including hepatitis A vaccine

包括甲肝疫苗

Let me show you the results

我给大家看一看结果

These are a little easier to interpret

相对于其他疫苗或免疫方面的问题

than some of the other vaccination and immunization issues

这个数据要容易理解得多

but if both groups are sleeping fine

如果两个小组的睡眠情况都正常

they get their flu shot

然后他们都接受了流感疫苗

the group that actually had good night sleep

那么接受疫苗注射之后

after the vaccine

睡了好觉的小组

had a much higher titer for Hep A vaccine

甲肝抗体的浓度

than the group that was left awake and kept awake

要高于注射流感疫苗之前

the whole night before their flu shot

整晚没有睡觉的小组的浓度

So it's a very critical issue with cytokine metabolism

所以睡眠对细胞激素的代谢

going on in sleep

起到了非常重要的作用

and sleep is very important for immune function

睡眠对免疫功能至关重要

Now I've actually looked at sleep in pregnancy

我还研究了怀孕时的睡眠

This was...we should talk about publication problems

我要讲讲这方面论文的发表问题

because I was publishing on sleep and pregnancy

我本来打算发表一篇睡眠和怀孕的关系的文章

and I sent this to a couple of OB journals

我把文章投给了一份产科方面的学报

and they said

结果他们说

I'm sorry

对不起

we don't have anybody

我们这里没有人能够审阅

who can review any papers on sleep for women

女性睡眠问题的文章

Could you suggest them review yours

你能不能建议他们审阅

It was very difficult to get this published

所以文章很难发表

But we looked at women during their third trimester

我们研究了孕妇在临产前3个星期

课程简介和演讲视频

课程简介
本套课程讲解了睡眠对健康的多重影响。睡眠不足会改变身体的内分泌系统，打破激素的平衡，扰乱大脑对食物的选择和摄取从而引发肥胖，严重影响胰岛素的平衡进而引发糖尿病。不同年龄段的人群有不同的睡眠需求，一般而言，年轻人的睡眠需求高于老年人，但所有成年人都应保证每天8小时的睡眠时间。老年人的睡眠时间减少并不是生理变化的自然结果，而是其他疾病造成的影响，衰老本身并不会降低睡眠需求。常见的睡眠障碍包括失眠、睡眠呼吸障碍、四肢不宁综合症、快速眼动期行为失调，患者需要就具体的睡眠障碍咨询专业的睡眠医生，确诊后有针对性的改善睡眠，进而提高整体的健康状况。不同的睡眠障碍有不同的治疗方式，但认知行为疗法是所有治疗方法的首选，其次是器械治疗、药物治疗以及外科手术治疗。患者应养成良好的睡眠习惯，培养“睡眠卫生习惯”，改善睡眠质量，尽量避免擅自用药和药物滥用。