These days, antibiotics are no silver bullet. In fact, if you get them in the hospital, you may end up with an additional infection. Like the bug Clostridium difficile, or C. diff — which infects more than 300,000 Americans a year and kills some 14,000. C. diff flourishes in the post-antibiotic, microbe-free landscape of your gut. But there is a way to stop it — a fecal transplant. That cocktail of microbes from a healthy person's gut can rein in a C. diff outbreak. The question is not eewww? It's: what are the transplant's active ingredients?
Well, one of them appears to be a bacterium called Clostridium scindens. Because in past studies, people and mice that harbored C. scindens were protected against a full-blown C. diff infection. So researchers dosed mice with the good guy, C. scindens, after a bout of antibiotics. And the treatment did indeed ward off C. diff, compared to a cocktail of other microbes, or nothing at all.
其中一种有效成分是一种叫做Clostridium scindens的细菌。因为，在以往的研究中，体内寄生着C. scindiens的人或老鼠能免于遭受艰难梭菌的全面攻击 。于是科学家给注射过抗生素的老鼠服用C. scindiens. 。与其他微生物的代谢物相比，或不用对比，我们就能知道这种疗法确实能够抵御艰难梭菌 。
C. scindens makes a living by breaking down bile, the researchers say, and it's those secondary products that seem to inhibit C. diff. The findings are in the journal Nature.
This work could lead to more targeted probiotic treatments. But study author Eric Pamer of Memorial Sloan Kettering Cancer Center says it's worth remembering that when it comes to microbes, the sum is often greater than its parts. "In some ways I would say this is far more complex than an orchestra, in that there are many more interdependencies, and many of which we just don't understand yet, but that are starting to be illuminated by ongoing work." Now, at least, we know one of the featured performers.
Unfortunately, there is no silver bullet to cure this desease.
Many people have begun looking for long-term ways to rein in spending.
Over time, the protein in the eggshell breaks down into its constituent amino acids.
Programs usually include an element of ongoing work.