(一).What's the matter with you? 你怎么了？
原音重现：

A：What's the matter with you?
你怎么了？
B: I think that food made me sick.
我好想食物中毒了。

(二).What's wrong with you? 怎么了？

原音重现：

A：You look terrible. What's wrong?
你的脸色非常不好，怎么了？
B: I haven't been able to sleep well.
我无法安睡。