科学美国人60秒:冷冻电镜技术获2017年诺贝尔化学奖
日期:2018-01-31 11:45

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This is Scientific American — 60-Second Science. I'm Steve Mirsky.
"The Royal Swedish Academy of Sciences has decided to award the 2017 Nobel Prize in Chemistry jointly to Jacques Dubochet, Joachim Frank and Richard Henderson...for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution."
Göran Hansson, secretary general of the Academy, at 5:53 this morning Eastern time.
Dubochet is honorary professor at the University of Lausanne in Switzerland. Frank is at Columbia University in New York. Henderson is at the Laboratory of Molecular Biology in Cambridge.
"The technique has transformed electron microscopy from a technique that could be used to just see the shapes, the outer shapes, of molecules into one that is now used to see the details, the atoms inside the molecules."

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2017年诺贝尔化学奖得主.jpg
Peter Brzezinski is a professor of biochemistry at Stockholm University and a member of the Nobel Committee for Chemistry.
"And the latest technical developments occurred very recently. So it's recent developments that you can actually see the details of these molecules. The technique is also relatively rapid, so once one has samples that can be studied the structure can be determined relatively rapidly. And this was exemplified last year when the structure of the Zika virus was determined in just a few months. And the structure shows the atomic details of the surface, which of course is important when developing drugs against the virus."
For an in-depth listen about the 2017 Nobel Prize in Chemistry, look for the Scientific American Science Talk podcast later today.
For Scientific American — 60-Second Science Science. I'm Steve Mirsky.

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参考译文

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这里是科学美国人——60秒科学i@00GpVyH,5!WBTYH0v。我是史蒂夫·米尔斯基=wN^K#jHf=^k-_
“瑞典皇家科学院决定将2017年诺贝尔化学奖共同授予雅克·杜波切特、阿希姆·弗兰克和理查德·亨德森,以表彰他们发明了冷冻电子显微镜,研发出能确定溶液中生物分子高分辨率结构的冷冻电子显微镜UA3=;IV~%)9XRPE。”
美国东部时间今晨5点53分,瑞典皇家科学院秘书长戈兰·汉森公布了获奖名单Fg7.@V-j;d4^pH2bw5B
杜波切特是瑞士洛桑大学的荣誉教授)pLW7B3b#+HJc8mSLq。弗兰克任教于美国哥伦比亚大学l;XK+57b7,p;fe,xU。亨德森在剑桥大学分子生物实验室工作bIlB)8fIhyB=Cd
此前电子显微镜只能看到分子形状和外观,而该技术使电子显微镜如今可以观察到分子详细情况和内部原子样貌rUvW;z|HbB0
彼得·布热津斯基是斯德哥尔摩大学的生物化学教授,同时也是诺贝尔化学委员会成员qEUHT&0=mXUC#AeY2|g
“这项最新技术刚刚研发出来#9Hr_j%Yz.N_cIH8。最近的发展使我们得以观察到这些分子的详细情况ZsMrGE0=+pwtujP。这项技术的见效速度相对较快,只要有可以用于研究分子的样本,就能相对快速地确定其结构riyc]V|tXo。去年有一个典型的例子,当时寨卡病毒的结构在短短几个月内就被确定了-OYkxw29a5r_-9~[-0x8。得出的结构显示了病毒表面的原子细节,这对于研究抗抵抗寨卡病毒的药物具有重要意义2%dwPnBoXhop.Z=。”
若想深入了解2017诺贝尔化学奖的相关信息,请关注今天晚些时候发布的科学美国人“科学对话”播客G7|I_TQMVPb7qC+S4#pX
谢谢大家收听科学美国人——60秒科学[LJsHLtVR9KfNa。我是史蒂夫·米尔斯基CUdTWdTL=(9-P*7P;AR

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译文为可可英语翻译,未经授权请勿转载!

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重点单词
  • determinedadj. 坚毅的,下定决心的
  • determinationn. (正式)决定,规定,决心,测定,定位
  • academyn. 学院,学术,学会
  • frankadj. 坦白的,直率的,真诚的 vt. 免费邮寄,使自
  • technicaladj. 技术的,工艺的
  • techniquen. 技术,技巧,技能
  • solutionn. 解答,解决办法,溶解,溶液
  • jointlyadv. 共同地,连带地
  • virusn. 病毒,病原体