gut-wrenching极度痛苦的，撕心裂肺的

He is the only one who has the gut to tell the truth.

他是唯一一个有勇气讲真话的人

The fact that his girlfriend broke up with him brought him the gut-wrenching feeling.

他女朋友和他分手这件事给他带来了极度的痛苦

It must have been gut-wrenching when your sister found out she had cancer. How did you deal with it

你妹妹得知她患癌症之后一定痛苦万分，你怎么安抚她的？

run its course按常规进行


We can't cure the disease; it must run its course.

我们治不了这种疾病，只好听其自然

No one would get involved in this case until the legal process had run its course

在法律程序结束之前，任何人都不能插手这件案子

It was gut-wrenching when they were told the disease could not be cured but to run its course.

当他们得知这种病不能被治愈，只能顺其自然时，他们悲痛万分

歌曲：i will be by leona lewis 爆料一下，这首歌的mv男主角是gossip girl中的帅帅的nate，花痴们可以去看看，嘿嘿