基因编辑有何用?
日期:2021-09-18 14:04

(单词翻译:单击)

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听力文本

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This is Scientific American's 60-second Science, I'm Steve Mirsky.

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这里是科学美国人——60秒科学系列,我是史蒂夫·米尔斯基To;)I)Uj%K

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On October 7, Jennifer Doudna and Emmanuelle Charpentier shared the 2020 Nobel Prize in Chemistry for the development of the gene-editing tool called CRISPR.

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10月7日,詹妮弗·杜德纳和艾曼纽·卡彭迪耶因开发了名为CRISPR的基因编辑工具,共同获得了2020年诺贝尔化学奖Flcr+wE2Z1J

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Last April,I spoke with Doudna at an event in Washington, D.C.

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去年4月,我在华盛顿特区的一次活动上与杜德纳进行了交谈alUuIMFOl%Lb

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A few months ago, I was at a talk about wine, and CRISPR came up. And it was it was an appropriate thing to bring up.

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几个月前,我参加了一个关于葡萄酒的演讲,CRISPR出现了B^LlwV~R(8KkM。这是一个合适的话题.MbeWx)7=CMKXwb(

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What is it like to be in this field right now, where everyone is talking about the work that you do and its implications?

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现在身处这个领域是什么感觉,每个人都在谈论你的工作及其影响?

Well, I have to say it’s very exciting.

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不得不说这很令人兴奋NUp(72OX)Vo0o[0[3o

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And as a scientist, it’s wonderful to see all the creative work that’s going on with gene editing.

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作为一名科学家,很高兴看到基因编辑方面的创造性工作zdTuPm-tS7ixT_XI

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It’s just a fascinating opportunity to see the innovation that people come up with when they have a tool that’s so broadly useful across biology.

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当人们拥有一种在整个生物学中如此广泛有用的工具时,这只是一个令人着迷的机会,可以看到人们提出的创新YcWO(2Yc]*4-bPtppY=L

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You do a million interviews, and you make a lot of public talks.

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你做了一百万次采访,以及开展了很多的公开演讲ok~HRAzu,y0abX.cB

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What do people not talk to you about that you would love to talk about regarding CRISPR?

关于CRISPR,有什么是人们不跟你谈的,而你又想谈的?

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Well, I think a lot of the discussion around CRISPR right now focuses on biomedical applications, which clearly are very exciting.

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我认为现在关于CRISPR的很多讨论都集中在生物医学应用上,这显然是非常令人兴奋的5pf,B^s~a7V

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I think something that I don’t hear as much—although I’m happy to hear that you had this conversation at a wine event—are the opportunities in agriculture.

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虽然我很高兴听到你们在葡萄酒活动上进行了这样的对话,但我觉得有些事情我并没有听到太多,那就是农业领域的机遇Z1|GHO|;,-w86H^6U

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I think they’re going to be huge.

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我想它们会很庞大hYMwX4i6#scF6

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And I’m really, really excited about the opportunities to use gene editing to create plants that will be drought-tolerant, pest-resistant, maybe more nutritious—give farmers opportunities to grow plants in environments where, in the past, they’ve been really challenging to grow.

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我对利用基因编辑创造出耐旱、抗虫害、可能更有营养的植物的机会感到非常兴奋,这让农民有机会在过去很难生长的环境中种植植物G2y4Qu2OpxWv=HAP%Su

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Yeah, the range of applications is just seemingly endless.

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是啊,应用范围似乎无穷无尽68AndkQpZVhmXP

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I think in the wine talk, we were discussing the threats to viniculture from global warming, right.

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我想在关于葡萄酒的演讲中,我们讨论了全球变暖对葡萄栽培的威胁t1r,pZUVUibq4

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And one of the possible applications there is to get the more heat- tolerant organisms to chip in, help the wine grapes.

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其中一个可能的应用是让更耐高温的有机体参与进来,帮助酿制葡萄UA)@]c=b@l]ECdh9DL

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You talk about the ethical considerations a lot.

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你说了很多道德方面的考虑^JyKkalCmLG

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Anything you’d like to discuss?

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你有什么想讨论的吗?

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I think the ethical considerations are incredibly important.

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我认为伦理考虑是非常重要的m|=5(81.[l

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People get very excited and concerned, appropriately, I think, on occasion about opportunities to use gene editing in systems where,

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人们非常兴奋和关心,我认为,适当地,偶尔在系统中使用基因编辑的机会,

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you know, we really need to be thoughtful about the responsible use—where there are great opportunities but also big, big challenges.

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你知道,我们真的需要考虑负责任的使用,那里有巨大的机会,但也有巨大的挑战uY5M*Id|tXv+;Fez!~|

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And of course, a very obvious one is in the human-germ-line-embryo editing but also, frankly, also in microbes and other organisms that could be released into the environment—using gene editing to spread genetic traits in a mode called gene drives.

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当然,一个非常明显的例子体现在人类-生殖系-胚胎编辑中,但坦白地说,也存在于可能被释放到环境中的微生物和其他有机体中 ——使用基因编辑,以一种叫做基因驱动的模式传播遗传特征3_#7~]8~!tRc9WZ=k__

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So that’s another area where there’s a lot of discussion about how careful we need to be.

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所以这是另一个我们需要谨慎讨论的领域QnHN#W4KC.yF_iMT

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How do we regulate this technology appropriately?

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我们如何适当地规范这项技术?

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How do we encourage science to advance but do it in a way that’s responsible?

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我们如何鼓励科学进步,但又以负责任的方式去做呢?

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Thanks for listening for Scientific American's 60-second Science. I'm Steve Mirsky.

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谢谢大家收听科学美国人——60秒科学Tz]385a##74。我是我是史蒂夫·米尔斯基,Rslf=6].Pu,5[]mC

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译文为可可英语翻译,未经授权请勿转载!

重点讲解

重点讲解:

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1.Innovation 革新,创新

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His greatest innovation was the use of interchangeable parts.

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他最伟大的创新是使用了可互换部件wb1ne8ro]bv=*tNf

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2focuses on 集中于

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Her literary criticism focuses on the way great literature suggestsideas.

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她的文学批评集中于伟大文学作品表达思想的方法@bUUbq6av=2SxL5I

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3.drought-tolerant 耐旱的

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This study has a guild meaning for drought-tolerant maize Germplasmselection.

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研究结果对大田玉米耐旱性筛选具有指导意义sXUU3L^xHS~a(w_1

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4.ethical 道德的;伦理的

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These shoppers are concerned with some ethical issues.

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这些购物者也关心一些道德问题NbxSl@NnA1

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