Enough is enough.
既然够了，那就要适可而止。

I'm fed up with 直译是我被喂饱了，可以想象是吃多了腻味，所以这句话意思是“令人厌恶，无法忍受”。
I'm fed up with his negative attitude.
我受够了他那种消极的态度了。

有关生活的谚语:
All work and no play makes Jack a dull boy.
只学习不玩耍，聪明孩子也变傻。
Care kills the cat.
忧虑伤身。
It's never too late to mend.
亡羊补牢，为时未晚。
The early bird catches the worm.
早起的鸟儿有虫吃。
Life is full of ups and downs.
人生有得意也有失意。