At sixes and sevens 乱七八糟
The whole schedule has been rearranged. I'm at sixes and sevens.
Mess n. 杂乱；脏乱；混乱局面
He makes a terrible mess when he's cooking.
My life is a mess.
Mess sth. up 把...弄糟；弄乱
I'm sorry that there are toys all over—the kids really messed your place up.
Screw sth. up 弄糟；弄坏
I screwed up my computer somehow—could you come and take a look at it?
Spoil v. 破坏；践踏
He tried not to let the bad news spoil his evening.