It's over.

我们缘分已尽。

We are history.

我们已经结束了。

We are done here.

我们再无瓜葛了。

We are not seeing each other any more.

我们不在一起了。

We borke up.

我们分手了。

We split up.

我们分手了。

Our relationship is over.

我们的关系到此为止。

We are strangers now.

我们现在形同陌路。

I gave up on him.

我离开了他。

We said good-bye to each other.

我们分手了。