Can you help me? I' m in a mess.

你能帮我个忙吗？我碰到困难了。

Will you do me a favor?

你能忙我个忙吗？

Give me a hand.

帮我个忙。

Will you do me a good turn?

请帮个忙行吗？

May I ask a boon of you?

我能请你帮个忙吗？

Please lend a hand with my book.

请帮我拿一下书。

I stand in need of help.

我需要帮忙。

Do me the service to go and fetch him.

请您帮我个忙，去找他来。

Excuse me. I was wondering if you could help me.

对不起，请问您能否能帮我个忙？