I understand an alcohol hangover all too well...
但我对醒酒过程的感觉很清楚
I try and avoid having them but when
我尽量避免有这种感觉 但是
I have one I know exactly what it is.
一旦我有了感觉 我知道它是什么样的
This is unknown and I'm not sure
而这个感觉是不清楚的
what to do to ease the symptoms.
我不能确认做什么能减轻这种症状
I'm also not clear about how its going to last.
我也不清楚这个感觉后面会怎样持续
There's a sort of discomfort and slight edge of worry
有一种不舒服并且轻微烦躁的感觉
that is borne out of that new substance.
是这种新药物带来的
I'm not in my hangover comfort zone.
我不是在醒酒的舒适状态中
If that makes sense.
如果这样讲有意义的话
That's one of the reasons alcohol is going to be such a hard act to follow
这就是为什么饮酒很难被规范的原因
but also why David has to keep trying.
同时也解释了为何大卫必须继续实验
Alcohols become the devil we know.
我们知道酒精变成了魔鬼
We've even forgiven it for the pain it causes.
我们甚至宽恕了它所导致的痛苦

重点解释：

1.clear about 明白

例句：She seems quite clear about her future curricula.
她对自己未来要学的课程看来很有把握。

2.sort of 有几分地

例句：That would sort of ruin the point.
那会有几分破坏的意图。

3.make sense 讲得通； 有意义； 言之有理

例句：Can you make sense of this poem?
你看得懂这首诗吗?