to knock oneself out努力（非正式）

英文释义
To work very hard to accomplish something; to make a strenuous effort.

例句
Working all weekend, day and night, the young marketing director really knocked himself out to make an impressive presentation at our meeting Monday morning.

经过了整个周末没日没夜的工作，这位年轻的营销总监终于努力在我们周一的晨会上做了一个精彩的演讲。