(单词翻译:单击)
Hey there! Welcome to Life Noggin.
大家好！欢迎来到脑洞大开的生命奇想。
Depression is a serious illness that affects over 300 million people worldwide.
抑郁症是一种严重的疾病，影响着全世界3亿多人。
While everyone feels sad sometimes, people with major depressive disorder — or clinical depression — can be down for weeks, months, or even years.
每个人都有感到悲伤的时候，而患有重度抑郁症的人——或者临床抑郁症——可能会持续数周、数月甚至数年情绪低落。
It's not something they can shake by changing their routine. For many, the activities that used to make them happy don't anymore.
这不是改变他们的常规活动就可以改变的事情。对许多人来说，过去让他们快乐的活动已经不能引起他们的兴趣。
They may feel hopeless and exhausted, have trouble sleeping, lose their appetite, or have a decreased libido.
他们可能感到绝望和疲惫，难以入睡，没有胃口，或者性欲减退。
It can be hard for them to get through the day or complete routine tasks. At its worst, depression can lead to suicide.
日常生活或完成日常任务对他们来说可能很难。最糟糕的是，抑郁会导致自杀。
I know that this is a delicate topic, so I teamed up my YouTube friend and licensed therapist Kati Morton!
我知道这是一个敏感的话题，所以我和我的YouTube好友和注册治疗师卡蒂·莫顿合作！
Kati, could you give us some insight onto why people get depressed? Sure thing! There isn't really one particular reason people slip into depression.
卡蒂，你能告诉我们为什么人们会抑郁吗？当然！人们陷入抑郁并没有什么特别的原因。
It can be triggered by an event or stress, but it can also start without a clear cause. Either way, it's real, and serious.
它可以由某些事件或压力引发，但也可能在没有明确原因的情况下出现。不管怎样，它是真实的，也是严肃的。
One in 10 people have been depressed at least once in their lifetime, and it's the leading cause of disability worldwide.
十分之一的人一生中至少有过一次抑郁，这也是世界范围内致残的主要原因。
For decades, scientists believed that the illness was caused by an imbalance of certain chemicals in the brain, like serotonin, that help regulate mood.
几十年来，科学家们一直认为这种疾病是由大脑中某些化学物质的失衡引起的，比如帮助调节情绪的血清素。
Many medications that treat depression boost these chemicals, but they often take weeks to work.
许多治疗抑郁症的药物会调节这些化学物质的分泌，但通常需要几个星期的时间才能生效。
This may be because the chemicals are actually helping build new neurons and connections in the brain.
这可能是因为这些化学物质实际上有助于在大脑中建立新的神经元和连接。
Several studies support this theory, suggesting that the root cause of depression could be problems with the brain's circuits.
一些研究支持这一理论，认为抑郁症的根源可能是大脑回路的问题。
One study showed that depressed people have weak connections in the parts of the brain associated with reward and memory, and strong connections in the areas associated with punishment.
一项研究表明，抑郁的人大脑中与奖赏和记忆有关的部分连接薄弱，而与惩罚有关的区域连接紧密。
Another study found hyperactivity in the areas controlling concentration and mood.
另一项研究发现，控制注意力和情绪的区域过于活跃。
This might be what causes negative thoughts to stay at the front of someone's mind, even when they try to push them away.
这可能会导致消极的想法一直停留在人的脑海中，甚至试图摆脱这些想法，也无济于事。
Scientists are now looking for treatments that target these circuits directly to provide better relief. But depression can be more than just bad feelings.
科学家们正在寻找直接针对这些回路的治疗方法，以提供更好的治疗方法。但是抑郁不仅仅是情绪低落。
It's also been linked to chronic pain, immune system problems, heart disease, and hormone imbalances.
它还伴随着慢性疼痛、免疫系统问题、心脏病和激素失衡。
In fact, physical symptoms are often the first sign of major depressive disorder.
事实上，生理症状通常是重度抑郁症的第一个症状。
In a study of roughly 1200 people who met the criteria for depression, nearly 70% went to the doctor for physical symptoms, not mental.
一项研究调查了1200名符合抑郁标准的人，其中近70%的人去看医生是因为生理症状，而不是精神症状。
So, does depression cause physical problems, or is it the other way around? Well, It may be both.
那么，是抑郁导致了生理问题吗？还是反过来呢？嗯，可能两者都有。
For example, researchers have long thought that stress can cause stomach issues, but there's also evidence that irritation in your gut can trigger mood swings.
例如，研究人员一直认为压力会导致胃部不适，但也有证据表明，肠道的刺激会引发情绪波动。
Since the mind and body are so closely linked, mental illness is often felt physically even though there is no illness in the body itself.
由于精神和身体紧密地联系在一起，即使身体本身没有疾病，精神疾病通常也能在身体上反映出来。
Those physical sensations are called psychosomatic symptoms.
这些生理感觉称为心身症状。
Some scientists believe that physical and emotional pain share similar pathways in the brain, and it's necessary to treat both types of symptoms to get relief.
一些科学家认为，身体上和情感上的疼痛在大脑中有相似的通路，因此缓解疼痛必须同时治疗这两种症状。
No matter how depression manifests, the most important thing is to get the right help.
无论抑郁症表现如何，最重要的是得到正确的帮助。
Many people suffer silently because they think admitting to depression is a sign of weakness. But it's not, and you are not alone.
许多人默默承受痛苦，因为他们认为承认抑郁是软弱的表现。但事实并非如此，你不是一个人。
Talking about it with a professional is one of the main things that can help, and most forms of depression are treatable.
与专业人士谈论抑郁症是最主要的有效方式之一，而且大多数形式的抑郁症是可以治疗的。
If you know someone who might need help, or if you need help now, you can check the links in the description for free resources.
如果您知道某人可能需要帮助，或者如果您现在需要帮助，您可以点击描述中的链接获得免费资源。
And please, speak to a professional. Depression can be very difficult to live with, but there are lots of ways to get help.
请向专业人士求助。抑郁是很难忍受的，但是有很多方法可以得到帮助。
Thank you so much to Kati for helping with this video! She's a great friend and is helping people every week on her youtube channel.
非常感谢Kati帮我制作了这个视频！她是一个很好的朋友，每周都在她的youtube频道上帮助别人。
So if you want to dive right in, I highly recommend starting here or click the link in the description.
所以如果你想直接进入，我强烈建议从这里开始或者点击描述中的链接。
You can see that if something is wrong in our brain, if we are feeling really down and out, that body aches might be common. We might wanna sleep a lot.
你可以看到，如果我们的大脑出了问题，如果我们真的感到沮丧，那么身体上的疼痛可能很常见。我们可能很想睡觉。
If you have any stories you feel comfortable with sharing, let us know in the comment section below.
如果你有任何觉得可以分享的故事，请在下面的评论区告诉我们。
As always, my name is Blocko. This has been Life Noggin. Don't forget to keep on thinking!
我是宝高，这里是脑洞大开的生命奇想。思考不要停！
