1. What seems to be the trouble is... 好像问题在于…….

What seems to be the trouble is that nobody knows how to operate this machine.
好像问题在于没有人知道怎样操作这台机器.

2. What surprised me is that...令我吃惊的是…….

What surprised me is that everybody seemed to be very indifferent to her.
让我吃惊的是每个人似乎对她都很冷淡. [ indifferent adj.不关心的;冷漠的]

3. What will you do if... 如果……,你会做什么

What will you do if such kind of thing happens to you 如果你碰到这样的事,你会做什么

4. What you have to do is... 你必须做的是…….

What you have to do is hand in your composition tomorrow. 你必须做的是明天交作文.

5. What would you say /think of... 你认为……怎么样

What would you say if the project will have to be postponed
如果这个项目不得不推迟你认为怎么样

6. When do you want me to... 你想让我在什么时候……

When do you want me to give you my final decision 你想让我在什么时候给你最后决定

7. When it comes to... 谈到……,./涉及到…….

When it comes to English, he's an expert. 在英语方面,他是个专家.

8. When will it be convenient for you to... 你看什么时候方便……

When will it be convenient for you to come to my home 你看什么时候方便来我家

9. Would you be so kind as to... 能否请你……

Would you be so kind as to get our board and lodging ready
能否请你帮我们安排好食宿 [ board and lodging:食宿]

10. Would you like to... 你想……吗

Would you like to join us We're sure you'll have a good time.
你想加入我们吗 我们相信你会玩得很开心的.