VOA慢速英语(翻译+字幕+讲解):美国批准首个针对埃博拉病毒的疗法
日期:2020-10-20 15:32

(单词翻译:单击)

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US Approves First Treatment for Ebola Virus
The United States Food and Drug Administration (FDA) has approved the world's first treatment for the deadly Ebola virus.
The treatment, Inmazeb, is a combination of three genetically-engineered antibodies. The company Regeneron Pharmaceuticals developed it to treat both young and old patients with the virus version called Zaire Ebola. It is the deadliest kind of Ebola known to infect humans. Zaire Ebola usually kills 60 to 90 percent of patients.
FDA officials announced the approval of Inmazeb on Wednesday.
The Zaire Ebola virus can spread easily through direct contact with body fluids of infected people or animals. Signs of the disease include increased body temperature, pain, stomach sickness, kidney and liver damage, and bleeding. People who provide care to infected individuals are at highest risk of contracting the virus.
Regeneron's drug was one of four tested during a Zaire Ebola outbreak in Congo between 2018 to 2019. The outbreak killed almost 2,300 people.
Regeneron received support from the U.S. National Institutes of Health and international health agencies.
The study involved 681 people infected with the virus. After four weeks, about one-third of 154 patients who received Inmazeb had died. Similar results were reported for a group that got a different drug. But, about half the patients died among the other two groups given one of the other two drugs.
The study ended early last year so all patients could get Inmazeb.

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埃博拉病毒.jpeg
Leah Lipsich leads Regeneron's infectious diseases program. She said, "When you have three drugs that bind to the (virus), there's a low probability that the virus can evade all of them."
Lipsich noted that the FDA's approval will make it easier for the company to get permission to use the drug during outbreaks in African countries.
George D. Yancopoulos is Regeneron's chief scientific officer. He said the drug maker is using the same technology to develop an antibody drug to treat COVID-19. He said in a statement, "we hope this will be one of many demonstrations of how the power of science can be successfully deployed against dangerous infectious diseases."
The antibody combination technology has also been used to develop drugs to treat HIV, the cause of AIDS. Regeneron and drug maker Eli Lilly are now asking the FDA to permit emergency use of experimental engineered antibody medicine to treat patients with COVID-19.
The FDA approved the first vaccine for Ebola last December. That drug, Ervebo, is made by Merck.
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参考译文

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美国批准首个针对埃博拉病毒的疗法
美国食品药品监督管理局(简称FDA)批准了全球首个针对致命埃博拉病毒的疗法3kVX*p=(UVP09DeR
这种被称为“银马泽伯”的疗法是三种转基因抗体的组合TGVQ9XV~bx。再生元制药公司开发了这种疗法,用于治疗感染扎伊尔型埃博拉病毒的年轻患者和老年患者g#]j4N|]+_ZNO。该病毒是已知感染人类的最致命的埃博拉病毒XX)_u)L[Kh.o+~。扎伊尔型埃博拉病毒通常会导致60%至90%的患者死亡r6Qa;)dL&5EY%9
美国食药监局官员周三宣布批准“银马泽伯”疗法f&75YB-psEHs#
扎伊尔型埃博拉病毒可通过直接接触受感染人类或动物的体液而轻松传播9i@d(_bY7XLbhq=。该疾病的症状包括发烧、疼痛、胃病、肾脏和肝脏损伤以及出血TbcZf[hagJOY]。为感染者提供护理的人员感染这种病毒的风险最高f.R,dF[pk;3^9k
再生元公司研发的药物是2018年至2019年扎伊尔型埃博拉疫情在刚果爆发期间测试的四种药物之一5K^fXKvO@F%。这次疫情导致近2300人死亡aJjIYifXwVOV|
再生元公司获得了美国国立卫生研究院和国际卫生机构的支持X@U;-YIZ-lqp[9^U
这项研究涉及681名病毒感染者|jTE,]UVnwq.t]。四周后,154名接受“银马泽伯”疗法的患者中有约三分之一的人死亡bMU6qj^lFbKvkw6Us。服用另一种药物的一组患者报告了类似的结果t*olI1J-qInil。但是,服用另两种药物之一的其他两组患者中有约一半人死亡%|FbfqwUC;6Wtb
这项研究于去年年初结束,因此所有患者均能获得“银马泽伯”疗法WA~JZ39ZL37aqo
莉亚·利普西奇负责领导再生元公司的传染病项目~9rlkHMQh5Om~,。她表示,“当有三种药物与病毒结合时,病毒对所有药物都免疫的可能性很低dU(-kO|stIvzSV。”
利普西奇指出,美国食药监局的批准将使该公司在非洲国家爆发疫情时更容易获得使用该药物的许可5C&wX7+pXaurxbp^o1
乔治·D·扬科普洛斯是再生元公司的首席科学官jkofMSY;8wT^BbS*)。他表示,这家制药公司正在使用同样的技术开发一种治疗治疗肺炎的抗体药物~fC]J%oUaa.a%ju0z;。他在声明中表示,“我们希望这将成为如何成功运用科学力量对付危险传染病的众多例证之一d=)KPV2!t(R9P&LGwv。”
抗体组合技术还被用于开发治疗艾滋病病毒的药物8G=8Q~q2[Z.S+-HDKiF。目前,再生元公司和制药商礼来公司请求美国食药监局允许紧急使用实验性转基因抗体药物治疗新冠肺炎患者Mt,U.^mFiSqqe
美国食药监局去年12月批准了首个埃博拉疫苗x%3Y&+E^LxZ9。这种名为Ervebo的疫苗由默克公司生产qrwR+~QOZB[kUJL1X*x
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译文为可可英语翻译,未经授权请勿转载!

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