日期:2018-03-12 09:35





Hari Sreenivasan: This week, the maker of Oxycontin, announced it is ending its marketing operation for the powerful opioid. Purdue Pharma is not giving up selling the highly profitable drug, but it will stop sending reps to doctors offices to drive sales of the addictive painkiller. Back in 2007, Purdue pleaded guilty to criminal charges of misleading the public about Oxycontin's addictive qualities and agreed to a civil penalty of nearly $635 million. This week's decision comes as Purdue and other opioid manufacturers are facing lawsuits from some 400 cities and states alleging they fueled addiction by misrepresenting the risks. Could Purdue's move change the course of America's opioid crisis? Lev Facher is a reporter with STAT News and joins me from Washington, D.C. tell me how significant this is?

Lev Facher: Symbolically this is huge. This is the company that really changed the paradigm for opioid use in the 1990s by aggressively marketing it to prescribers. The fact that Purdue has decided it's no longer going to go into doctor's offices an push this drug is really symbolic of where the country currently is in terms of considering the opioid epidemic a public health crisis and in terms of recognizing the potential harmful characteristics of drugs like Oxycontin.


Sreenivasan: What is the correlation between marketing them less and less of them being available on the street?

Lev Facher: Obviously, marketing drugs less should correspond to fewer sales. That said, this is not really a preemptive move. This is after years of declining Oxycontin sales. The Centers for Disease Control and Prevention issued recently new and much stricter guidelines for opiod prescription, so prescriptions are down, public awareness of the addictive qualities of these drugs is way up. And while there's still legitimate medical need and while prescriptions are going to continue, this is a move that more corresponds to a decline in sales than one that should fuel one.

Hari Sreenivasan: What are the factors that can actually decrease opioid consumption overall, or over prescription? It seems there is a tremendous amount of power in the hands of the insurance companies that choose to say that it's okay to prescribe these and that we'll pay for them.

Lev Facher: Yeah, and both insurance companies and public health providers like medicaid and medicare have taken steps, a variety of steps recently to reduce prescriptions and increase incentives to prescribe nonopioid, non-addictive pain killers. But again the marketing, I think, is less of something that is going to drive fewer prescriptions and more on Purdue's front on something that is meant to really change the narrative. They've been taking out full page ads in newspapers. They have been really trying to get out in front of the fact that they are increasingly viewed as a culprit. You mentioned the settlement in 2007. They are in talks to settle many of those other lawsuits from states and municipalities that you mentioned. So in terms of marketing, it's unclear of what level of impact that's going to have on prescription levels. But this comes amid really a sea change in the way physicians are prescribing opioids to begin with. And that has been happening over the last several years along with actions from the drug enforcement agency. A lot of different government agencies that are really taking steps to make sure that these drugs are used much less liberally.

Hari Sreenivasan: All right, Lev Facher of STAT News joining us from washington, thanks so much.

Lev Facher: Thanks, Hari.





1.way up 在更高处
We started from the bottom and we had to work our way up to the top.


2.take out 办理
They find a house, agree a price, and take out a mortgage through their building society.
3.in talks 商讨
The new fixture package has been hammered out by the Premiership clubs in talks over the last ten days.


4.along with 一起
He came along with some friends.




哈里·斯瑞尼瓦桑:本周,奥施康定制药商宣布,由于阿片药效强劲,该公司将停止对本药进行市场营销DHW(_9GP~(。普度制药公司不是要放弃如此高盈利的药物,但它将停止向医生办公室派送医药代表,推销这种致瘾止痛药*I0W@3b+*-M%v9#d31。2007年,普度制药承认,其在奥施康定的致瘾性上误导了公众,并接受了高达63,500万美元的民事罚款RxB=H08ko)V_O%%。本周此项决定的公布,正值普度及其他阿片制造商面临诉讼之时,大约400个城市及州份宣称这些公司故意误传该药物的成瘾风险,从而加剧了人们对它的药物依赖qXY@VmBe)=CkN#98h~j。普度此举可以改变美国的阿片危机进程吗?来自华盛顿特区STAT News的列弗·法彻,请告诉我此事有什么重要意义?






斯瑞尼瓦桑:好的,做客节目的是来自华盛顿特区STAT News的列弗·法彻,非常感谢.xch1)Tg,De&8V




  • potentialadj. 可能的,潜在的 n. 潜力,潜能 n. 电位,
  • availableadj. 可用的,可得到的,有用的,有效的
  • epidemicn. 传染病,流行病 adj. 流行的,传染性的
  • profitableadj. 有益的,有用的
  • characteristicsn. 特性,特征;特质;特色(characteristi
  • penaltyn. 处罚,惩罚
  • criminaladj. 犯罪的,刑事的,违法的 n. 罪犯
  • preventionn. 阻止,妨碍,预防
  • settlev. 安顿,解决,定居 n. 有背的长凳
  • varietyn. 多样,种类,杂耍