Daytime Wounds Heal Faster
A new study suggests that the timing of a wound affects the speed at which it heals.
Wounds suffered during the day heal around 60 percent faster than those sustained at night.
The study showed how the body's circadian rhythm controlled the healing of wounds. The circadian rhythm is like a clock or timer. It tells our bodies when to wake up, eat and sleep in a cycle -- a series of activities that repeat themselves day after day. Each cycle lasts about 24 hours.
In the study, researchers found that skin cells moved faster to repair wounds sustained during the day. Their findings were published in the journal Science Translational Medicine.
The researchers examined cells, mice, and burn injury databases. Specifically, their investigation found the following information: Night-time burns - burns suffered between 8 o'clock at night and 8 o'clock the next morning - were 95 percent healed after an average of 28 days.
But after an average of 17 days, daytime burns - burns sustained between 8 o'clock in the morning and 8 at night – were 95 percent healed.
In other words, nighttime injuries took an average of 11 days longer to heal.
The scientists say that circadian clocks play an important part in healing. Circadian clocks control many cells in the body and affect many biological processes, including sleeping.
John O'Neill was a co-leader of the study. "This is the first time that the circadian clock within individual cells has been shown to determine how effectively they respond to injuries," he said.
O'Neill added "We consistently see about a two-fold difference in wound healing speed between the body clock's day and night. It may be that our bodies have evolved to heal fastest during the day when injuries are more likely to occur."
Wounds are very costly to treat. Worldwide, billions of dollars are spent every year on wound-treatment services. In Britain's National Health Services, for example, such services cost around $6.56 billion per year. Experts says the high costs result, in part, from a lack of drugs that speed up the closure of wounds.
The findings, if confirmed by other studies, could have important implications for surgical operations and wound-healing medicines.
John Blaikley works at Britain's University of Manchester. He said the new study's findings could help scientists develop better drugs. The findings, he added, could also help doctors understand the best time of day to do a surgery or give medicine.
I'm John Russell.
1.wake up 苏醒
A cool shower wakes up the body and boosts circulation.
2.a series of 一系列的
A series of technical foul-ups delayed the launch of the new product.
3.burn injury 烧伤
Four fatalities, one serious burn injury, and horrible memories of a tragedy that should have never happened.
4.an average of 平均
The boats remain at sea for an average of ten days at a time
5.The scientists say that circadian clocks play an important part in healing.
play an important part in 发挥重要作用
He play an important part in the development of the French nuclear power programme.
The detection of human physical signals play an important part in modern medical treatment and research.
6.Experts says the high costs result, in part, from a lack of drugs that speed up the closure of wounds.
in part 某种程度上；部分原因是
In part this attitude was due to fear of trade union and employee reactions.
Their harmonious relationship resulted in part from their similar goals
该研究展示了人体的昼夜节律如何控制伤口的愈合速度 。昼夜节律就像钟表或计时器 。它会周期性地提示人体苏醒，进食，睡觉的时间——这些活动每天都会重复进行 。每次循环周期为24小时 。
在这项研究中，研究人员发现，皮肤细胞能够更快地修复白天的伤口 。他们的研究发表在《科学转化医学杂志》上 。
研究人员对细胞、老鼠和烧伤损伤数据库进行了检查 。具体来说，他们的研究发现了以下信息：95%的夜间烧伤（即晚8点到次日早8点），其平均的愈合周期为28天 。
科学家指出，昼夜节律在治疗方面有着重要的作用 。昼夜节律可以控制人体的许多细胞并影响许多生物过程，包括睡觉 。
约翰·奥尼尔（John O’Neill）是该研究的联合负责人 。他说，“这项研究首次显示出，个体细胞内的昼夜节律能够对伤口作出有效反映” 。
奥尼尔还表示：“我们不断了解到，昼、夜时伤口的愈合速度有着两倍的差异 。或许是因为白天更容易受伤，因此人体的愈合速度也就更快 。”
伤口治疗的价格不菲 。每年全球用于伤口治疗的费用高达数十亿美元 。以英国国民医疗服务体系为例，其每年在伤口治疗方面的花费达65.6亿美元 。专家称，如此高昂的花费部分原因是缺乏加速伤口愈合的药品 。
约翰·布莱克力（John Blaikley）就职于英国曼彻斯特大学 。他表示，新研究发现可以帮助科学家发明更有效的药物 。他还指出，这一发现也能帮助医生确定最佳手术时间或最佳用药时间 。